The organization chart of the laboratory involves well-defined responsibility levels. Firstly, the laboratory relies on the direction of the Director General (DG). The Director-General is the chief executive officer of INL as well as its legal representative.

He or she reports to the Council and directs the laboratory acting under the auspices of the INL Staff Rules & Regulations, INL financial administration rules and INL statutes. The DG counts on the support of the Deputy Director General (DDG), who is also designated by the Council.