Project Title: LOC4BIO - Self Assembled Nanostructures for biomed, food quality and environmental applications

The goal of this project is to develop a new generation of Lab-on-Chip (LOC) devices, which result from the integration of diverse state-of-the-art micro fabricated components, taking advantage of the small scale and allowing unprecedented automation and performance.

A number of relevant topics in the biomedical, food and environmental areas are identified as target applications to be addressed.

In the biomedical field both in-vivo implantable devices and ex-vivo diagnostic platforms are thought. Implantable devices will target drug-delivery at precise locations inside the body, perform neurological and cardiac stimulation and signal reading, and disease monitoring (e.g. cancer, cardiovascular insufficiency). In the case of ex-vivo devices, two types of platforms will be developed; i) one based on DNA- or protein-based chips for static detection and monitoring of specific biomarkers related with actual diseases (e.g. cancer, neurodegenerative, auto-immune); ii) other based on dynamic measurements for cell separation and counting. 

In the case of applications in the food and environmental fields, LOC devices will be intended for the accomplishment of multiplexed assays in chemical and microbiological analysis of water resources and processed or raw alimentary products.


Project financed by: ON2 - O Novo Norte – The north regional operational programme

Priority Axis I – Competitiveness, Innovation and Knowledge.

Call: SAESCTN-PIIC&DT/1/2011 

Total budget: 842K€

Financing: 775K€