nanomedicine_(1)

Therapeutic Tools and Methods

RESEARCH

DEPARTMENTS
Lifescience
NANOHEALTH
RESEARCH GROUPS
NANOHEALTH_DIAGNOSTIC
NANOHEALTH_THERAPEUTIC
NANOHEALTH_SYSTEMBIOLOGY
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DESCRIPTION

In the therapeutic tools and methods group we envisage new approaches towards innovative drug delivery solutions. These approaches can either rely on (i) bottom-up strategies, like the self-assembly of building blocks (e.g. lipids, polymers) into nanocarrier particles for the delivery of drugs and genes, or (ii) on top-down micro/nano-fabrication of medical devices for sustained drug release. A combined approach (iii) is also used, where microdevices are developed for directing self-assembly of lipid-based nanocarriers with enhanced functions, not achievable with conventional methods.

While for the time being most of the emphasis is put on the development of such enabling technologies for drug/gene delivery, the long term goal is to work together with clinicians and use these technologies in the development of treatments for ageing-related diseases.

RESEARCH PROJECTS

1- Nanocarriers for drug and gene delivery

TherapeuticProject1

2- Development and Application of Microneedles to Induce Immunotolerance in the Context of Multiple Sclerosis
[Nanotrainforgrowth program – COFUND Marie Curie Action, European Commission’s 7th Framework Programme].

TherapeuticProject2

PUBLICATIONS

2016

BFB Silva C Rodriguez-Abreu, Vilanova

Recent advances in multiple emulsions and their application as templates (Journal Article)

Curr. Opin. Colloid Interface Sci, 25 (98-108), 2016.

(Links | BibTeX)

LR Pires F Marques, JC Sousa Cerqueira Mendes-Pinto

Nano- and micro-based systems for immunotolerance induction in Multiple Sclerosis (Journal Article)

Human Vaccines and Immunotherapeutics , 12 , pp. 1886 -1890, 2016.

(Links | BibTeX)

RESEARCH

DEPARTMENTS
Lifescience
NANOHEALTH
RESEARCH GROUPS
NANOHEALTH_DIAGNOSTIC
NANOHEALTH_THERAPEUTIC
NANOHEALTH_SYSTEMBIOLOGY