Nanomedicine Optical Scattering Theory

Several core-shell nanoparticle material systems have proven interesting to the nanomedicine arena due to their potential use as biomarkers in nanomedicine. This project aims to improve the understanding of the optical scattering of such core-shell nanoparticles near a substrate from a theoretical point of view.

One can for example consider liposomes as core-shell particles whereby the core is composed of an aqueous medium and the shell of a lipid bilayer that optically can be represented by an anisotropic dielectric model. In 2014, the Applied Nano-Optics Laboratory introduced a theoretical framework to calculate the optical scattering of such core-shell particles near a substrate. [1]

Furthermore, we are interested in expanding the knowledge of surface scattering of metallic core-shell particles near a substrate and develop strategies for implementation in a biosensing context.

For this project we gratefully acknowledge aid recieved through the SCATMEC polarized light scattering software library developed by Dr. Thomas A. Germer at NIST. [2]




1. De Beule PAA. Surface scattering of core–shell particles with anisotropic shell. J Opt Soc Am A. 2014; 31(1):162. doi:10.1364/JOSAA.31.000162.

2. SCATMECH Project Home Page 

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