Nanomedicine Applied Nano-Optics

Our mission is to develop new optical technology contributing to the solution of outstanding questions in the life sciences. Within a multidisciplinary research environment, the Applied Nano-Optics laboratory members aim to develop and apply a variety of microscopic imaging tools to study lipid bilayers, liposomes and nanoparticle-lipid complexes within a biological native environment in real-time. Having filed two European patent applications, we also actively promote the introduction of our research ideas into the market place.

Developments introduced by the laboratory include a new type of combined optical and scanning probe microscopy [1], improved imaging ellipsometry at the solid-liquid interface [2], and the development of an analytical theoretical framework for analysing visible light scattering of liposomes near a substrate [3].




1. Miranda A, Martins M, De Beule PAA. Simultaneous differential spinning disk fluorescence optical sectioning microscopy and nanomechanical mapping atomic force microscopy. Rev Sci Instrum. 2015; 86(9):093705.

2. Miranda A, De Beule PAA. Microscopic thin film optical anisotropy imaging at the solid-liquid interface. Rev Sci Instrum; 2016:87(4):043701.

3. De Beule PAA. Surface scattering of core–shell particles with anisotropic shell. J Opt Soc Am A. 2014; 31(1):162.


Group manager Pieter De Beule