Environment monitoring, security and food quality control Detection of food-borne pathogens using a magnetoresistive platform
Traditionally, the identification of bacterial species has been achieved using classical culturing methods, coupled to morphological, physiological, and biochemical characterization techniques that are time consuming. In the last decades, the progress of biomolecular analytical tools together with informatic tools has given rise to faster methods that show good sensitivity to certain analytical problems.
However, there is still the need of tools that allow to perform real time detection of bacteria in different research fields, including food and environmental safety, medicine, etc, at the required levels. In order to overcome this difficulty, the aim of this project is to use magnetoresistive chips coupled to a portable nanotechnology platform that allows to perform the detection of multiple bacteria in a single chip.
The approach followed is based on coupling signal amplification schemes without PCR (Polymerase Chain Reaction), to magnetic particles that will provide the signal to be monitored with the magnetoresistive platform. Simultaneous detection of six bacteria in parallel would be possible through the immobilization of different probes onto the sensing areas of the microchip.
Group manager Maria Teresa Fernández-Argüelles