Nanomedicine (NM)’s research focuses on the development of diagnostic and therapeutic approaches towards an early and unequivocal diagnosis and treatment of cancer, inflammatory and neurological diseases. NM works in close collaboration with the clinic to enable translational medical research and to approach the end-user, in an attempt to offer a better prognosis and personalized treatment. To this aim, NM covers from fundamental research on the identification and validation of diseases’ biomarkers and cellular interactions, to a more applied cross-disciplinary research focused on the development of technologies and nanostructures (inorganic, organic, hybrid) for precision disease diagnosis, therapy and theranostics, ranging from low to high technology readiness levels (TRLs).
NM field of action comprises in vitro (2D, 3D, OoC), ex vivo and in vivo experimentation and evolves in the frontier between Chemistry, Materials Science, Biophysics, Engineering and Biology, always within an international framework.
Nanomedicine evolves in the frontier between different disciplines of knowledge, such as chemistry, materials science, physics and biology, always within an international framework.
1- Engineering of advanced (magnetic) nanostructures towards disease-specific imaging and stimuli-triggered therapy and theranostics. Led by Juan Gallo/Manuel Bañobre.
2- Soft self-assembled nanostructures for gene/drug delivery. Led by Bruno Silva.
3- Mechanisms of disease and identification of molecular biomarkers for the development of new diagnostic technologies and therapies. Led by Inês Mendes Pinto.
4- Development of innovative bioengineered tools to study cellular interactions at the tumor microenvironment and metastatic sites. Led by Marta Oliveira.
Claudia Botello (in collaboration with Prof. José Teixeira at U.Minho)
Lorena G. Hevia
PhD student (2014-2017)