INL advances skin engineering with the European network NETSKINMODELS

January 31, 2025

Advances in skin engineering research are being made at the INL as part of the NETSKINMODELS COST Action. This European network is dedicated to advancing skin engineering and modelling by developing improved cell-based and computational skin models, with the goal of reducing reliance on animal testing.

Ana Ribeiro, staff researcher at INL, highlights the contributions of Alfaro-Moreno’s research group: “At INL, we are developing skin-on-chip models, which are advanced microfluidic devices designed to replicate the structure and function of human skin. These models have the potential to transform research by providing more reliable and human-relevant data while supporting the 3Rs principle: reducing, refining, and replacing animal testing.”

Samantha Costa, one of the next-generation researchers benefiting from the NETSKINMODELS educational initiatives, has joined INL for her PhD research. Samantha’s work takes a further step towards the practical applications of these models, from testing cosmetics and nanoparticle safety to skin microbiome interactions. By focusing on sustainable and ethical research practices, Samantha concludes that “INL’s innovations aim to benefit science, industry, and society.”

“This work not only advances dermatological research but also helps prepare the next generation of scientists,” adds Ana Ribeiro. “Through initiatives like NETSKINMODELS, we are ensuring that Europe remains at the forefront of skin model innovation.” With scientific developments and a commitment to collaboration, INL researchers are playing a vital role in shaping the future of skin engineering research.

Text by Catarina Moura
Videography by Catarina Moura & Rui Andrade
Photography & digital media edition by Rui Andrade