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Sinfonia Project Concludes with a Resounding Success at the II ‘Total-Nanosafe’ International Conference in Braga

Sinfonia Project Concludes with a Resounding Success at the II ‘Total-Nanosafe’ International Conference in Braga

Braga recently hosted the closing event of the Sinfonia Project, where over 100 participants celebrated the successful culmination of a four-year journey dedicated to advancing nanosafety. The II ‘Total-Nanosafe’ International Conference served as the platform for this milestone, bringing together global experts to explore the intersection of nanotechnology, human health, and environmental impact. Pioneering Discussions in Nanosafety This year’s conference provided a comprehensive view of the latest nanosafety advancements, featuring discussions on nanotoxicology, organ-on-a-chip models, in vitro-in vivo bridging, in silico methods, and the environmental impact of nanomaterials. The event highlighted key trends shaping the future of nanosafety, underscoring a commitment to safe and sustainable nanotechnology development. Conference Highlights The conference opened with a welcome cocktail on November 6, followed by sessions on November 7 and 8. Professor Ulla Vogel from Denmark’s National Research Centre for the Working Environment delivered an impactful keynote on nanoparticle toxicology, focusing on occupational health risks related to nanoparticles, including cancer, cardiovascular disease, and fertility impacts. Presentations from INL and other leading institutions covered diverse research topics, such as the effects of silver nanoparticles on lung-barrier function, skin-on-chip safety models, and the impacts of black carbon on aging. These studies highlighted the scope of nanosafety […]

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INL’s Commitment to Science Outreach: New Board Games Illuminate Nanosafety and Air Quality Awareness for Young Audiences

INL’s Commitment to Science Outreach: New Board Games Illuminate Nanosafety and Air Quality Awareness for Young Audiences

INL – The International Iberian Nanotechnology Laboratory continues to champion science outreach and education by introducing two innovative board games: The Life Cycle of Nanomaterials and Clean Air in School! Play & LEARN. These games, developed through INL’s projects—SiNfONiA, LEARN, and SbDToolbox—reflect INL’s enduring commitment to bridging the gap between complex scientific research and accessible learning for younger audiences and by it’s commitment to science outreach by illuminating nano safety and air quality awareness for young audiences. These games embody INL’s goal of making science both engaging and educational, fostering a new generation’s awareness of environmental safety, health, and nanotechnology’s impact on daily life. Through these immersive tools, INL emphasises that scientific understanding is not only the domain of researchers but also a vital area of knowledge for the broader community. “The Life Cycle of Nanomaterials“, Bringing Awareness of Materials’ Lifetime Supported solely by INL through the SiNfONiA and SbDToolbox projects, The Life Cycle of Nanomaterials board game provides players with a comprehensive understanding of nanomaterials’ journey from creation to potential environmental and health impacts. SiNfONiA, spearheaded by the Alfaro-Moreno Group, is dedicated to advancing research in nanosafety and enhancing INL’s capabilities in this field. In parallel, the SbDToolbox project addresses the critical need for […]

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Filipa Lebre: Exploring the Frontier of Nanosafety

Filipa Lebre: Exploring the Frontier of Nanosafety

Filipa Lebre is a Research Fellow in the Nanosafety Research Group at INL, and her research focuses on the complex interactions among the immunological system and different organs, using novel technologies and in-house developed systems. Filipa has a background in Pharmaceutical Sciences and holds a PhD in Pharmaceutical Technology from the Faculty of Pharmacy, University of Coimbra, focused on the development and optimization of a polymeric nasal vaccine against hepatitis B to be used for mass immunization. She moved to Ireland during her postdoc to conduct her research at the interface between biomaterial and immunology, studying key aspects of immunomodulation by a relevant spectrum of materials with applicability in the regenerative medicine field. Could you share with us your professional trajectory and what inspired you to embark on a career in nanosafety? I’m very curious by nature and always had this passion and interest in science. When I did my degree in Pharmaceutical Science, I was fortunate enough to find a teacher who was working in the vaccine field and made me realize how I could use my passion to impact millions of lives. That was when I started to work with nanoformulations. I obtained my PhD in formulation development, […]

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Sadaf Almas, effective audit facilitation and continuous improvement initiatives

Sadaf Almas, effective audit facilitation and continuous improvement initiatives

We aim to shine a spotlight on the exceptional achievements of women at INL spanning different fields and career stages. Join us as we honour their accomplishments, share their stories, and ignite inspiration for the upcoming generation of female scientists. Meet Sadaf Almas. She works as a Quality systems Assistant in the Quality and Coordination unit at INL and she coordinates and inspects the core departments at INL to ensure the quality management systems consistency in terms of quality, validity, and reliability with study bases, facility-based and process-based approaches. Can you give us an update on what you’re currently working on? In my role within the Quality department, I play a crucial role in ensuring adherence to Good Laboratory Practice (GLP) standards, particularly in the context of Nanosafety laboratories. My primary responsibility revolves around facilitating GLP audits, employing principles established by the Organisation for Economic Co-operation and Development (OECD). First and foremost, I work closely with Nanosafety to develop comprehensive audit schedules aligned with OECD guidelines. This involves collaborating with INLers to ensure that all pertinent aspects of GLP are covered, from facility infrastructure to standard operating procedures (SOPs) and data management protocols. Before conducting audits, I review existing documentation […]

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Wrapping Up 2023: Research

Wrapping Up 2023: Research

2023 has been a busy year for the INL Community. This week we take a look at some of this year’s highlights and achievements regarding our projects, and the latest research developments. Even with all the changes, INL persisted in performing interdisciplinary research and deploying and articulating nanotechnology for the benefit of society addressing society’s grand challenges.  Here’s a comprehensive wrap-up of the key moments that defined the past 12 months. INL inaugurates state-of-the-art Cryo-Electron Microscope that helps to study new diseases Analysing biostructures down to the atomic level can help to study diseases such as Alzheimer’s or cancer, as well as to develop new therapies. This new type of investigation is now possible from Braga, thanks to the new electronic cryogenic microscope installed at INL – International Iberian Nanotechnology Laboratory. The acquisition of this equipment is part of the creation of the CryoEM-PT National Network, “an electron microscopy network for life and health sciences”, explains Paulo Ferreira, scientific coordinator of this initiative that opens doors to researchers and companies in Iberia, allowing easy access to state-of-the-art infrastructure and technologies. Read the full update >> ATLANTICLAM, brings Euro-native clam species from ‘farm to fork’ INL – International Iberian Nanotechnology Laboratory […]

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Recent research reveals neuro-behavioural changes associated with exposure to diesel exhaust particles

Recent research reveals neuro-behavioural changes associated with exposure to diesel exhaust particles

Air pollution is known to increase the likelihood of neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease. However, the exact mechanism involved in this relationship remains poorly understood. Diesel exhaust particles stand out as a prominent air pollutant with proven human carcinogenic properties, posing significant health risks, especially in the context of neurodegenerative diseases. Nivedita Chatterjee, a researcher from the Nanosafety research group at INL, is studying how diesel exhaust particles affect neurodegeneration, i.e. the slow and progressive loss of neurons. The INL team found that exposure to diesel exhaust particles causes significant neuro-behavioural alterations. Ernesto Alfaro-Moreno, Nanofatey research group leader explains that “this research work was developed under the project iCare – one of the objectives of this EU-funded project is to develop an integrated model system that can characterise and predict the potential impact of nanomaterials on brain health, thereby preventing nanomaterials toxicity”. Nivedita adds “to establish these models, we use Caenorhabditis elegans, often referred to as C. elegans, which is a very small and transparent roundworm that has been extensively studied in the field of biology. The knowledge gained from these studies on C. elegans often has broader implications for understanding more complex organisms, including humans.” The […]

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Investigating Air Quality in Schools with Advanced Sensors and Innovative Strategies

Investigating Air Quality in Schools with Advanced Sensors and Innovative Strategies

The LEARN project team is focused on understanding how air quality in schools affects children’s learning abilities. This unique EU-funded project aims to overcome existing technological barriers and develop new sensors to detect harmful air pollutants like volatile organic compounds and ultrafine particles. By measuring and studying indoor and outdoor air pollutants, as well as biomarkers of exposure, the researchers will assess their impact on children’s cognition. To achieve the project’s goals, a diverse team of leading researchers from various fields, such as environmental epidemiology, toxicology, air quality, systems biology, engineering, and social sciences, was assembled. To further explore these effects, INL researchers are using C. elegans as biosensors. Nivedita Chatterjee, who works in the Nanosafety research group, explains that “at INL, we set up a non-mammalian alternative model to study toxicity, development and behaviour, and we have been obtaining fascinating results. This will help us to better learn the effect of air pollutants on children’s health“. With LEARN‘s scientific achievements, we will have long-term impacts on indoor air quality technology, significantly improving the quality of life for children in Europe and leading to positive changes in society and the economy. Learn more about LEARN project and follow the project on social […]

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