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Exploring nanotechnology for the health of intestinal microbiota

Exploring nanotechnology for the health of intestinal microbiota

Researchers at INL are using nanotechnology to develop functional foods that can be consumed by people with food intolerances and allergies. Ana Isabel Bourbon, from the Food Processing and Nutrition research group, explains: “Our society is increasingly changing its eating habits and this has several effects on the intestinal microflora. When eating daily, people are subjected to increasing amounts of different compounds. This promotes microbial changes over the years, which causes diseases that previously did not exist, such as intolerances and allergies, to appear. Trying to understand how we can reduce these intolerances in the future is one of our group’s objectives”. In this context, INL researchers are creating foods with added nutritional value using nanotechnology. The team develops nanostructures enabling the encapsulation and incorporation of active compounds, such as vitamins and antioxidants. The goal is to ensure that, after ingestion, these compounds reach the bloodstream in sufficient quantities to have a positive impact on the consumer. However, obtaining information about the behaviour of these nanostructures during digestion and their effects on intestinal health poses a challenge. The Healthy-Gut project aims to address this gap by evaluating the behaviour of encapsulated systems using in vitro cell models. These models mimic […]

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Nanotechnology uncovering the hidden secrets of cancer

Nanotechnology uncovering the hidden secrets of cancer

Metastasis, the spreading of cancer cells to other parts of the body, contributes to 9 out of 10 cancer-related deaths. However, the intricate mechanisms triggering this process remain a mystery. 3DSecret is on a mission to change that. The European consortium 3DSecret, coordinated by INL researchers from the Medical Devices research group, is approaching metastasis in a new way, focusing on single cells and aiming to uncover hidden patterns that can predict and forecast how cancer spreads. “By studying individual circulating tumour cells, or CTCs, 3DSecret hopes to transform how cancer is diagnosed and/or treated, making significant strides in clinical sciences”, says Miguel Xavier, technical coordinator of the 3DSecret project. In response to this challenge, 3DSecret has outlined specific objectives. At the forefront is the development of the ‘3Dsecret-chip,’ a sophisticated tool designed to facilitate the controlled creation of 3D cancer cell models from individual cells. This innovative approach promises reproducibility and precision, enhancing one’s ability to examine the details of cancer cell behaviour. Furthermore, 3DSecret is incorporating ‘SERS metabolomics profiling’, an advanced technology providing continuous insights into the growth kinetics of these 3D cancer cell models. Sara Abalde-Cela, leader of the Medical Devices research group and coordinator of the […]

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Looking inside a solar cell

Looking inside a solar cell

In a ground-breaking study published in Nature Energy, researchers from the Nanostructured Solar Cells group have unveiled critical insights into the optimisation of thin-film solar cells, shedding light on methods to enhance their efficiency and pave the way for more cost-effective electricity generation. Photovoltaic power conversion utilising polycrystalline light-absorbing semiconductors has long been recognised for its potential to revolutionise solar energy. Among these technologies, polycrystalline CIGS (copper indium gallium selenide) stands out as a high-performing option, and recent advances have propelled its efficiency even further through an alkali-fluoride post-deposition treatment, which elevates the charge-carrier concentration. However, the team led by Sascha Sadewasser discovered a previously overlooked challenge in the application of this treatment – inhomogeneities in the conductivity of individual material grains, which they trace back to the charge-carrier concentration. This revelation has significant implications for the efficiency of solar cells and their overall performance. Using an emerging conductive atomic force microscopy tomography technique, the research team at INL literally scratched away material layer by layer, generating three-dimensional conductivity maps. A detailed analysis of these maps provided for a sub-micrometre scale visualisation of the carrier concentration grain by grain, allowing for a detailed look into the inside of the solar […]

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Wrapping Up 2023: Events

Wrapping Up 2023: Events

As we bid farewell to 2023, it’s time to reflect on the significant events that shaped the year at INL – International Iberian Nanotechnology Laboratory. The INL team worked incredibly hard throughout 2023, bringing all our events to life. In 2023, we opened our doors to almost 5000 people across 50 events. Each event contributed uniquely to the vibrant diversity of experiences at INL, and we are grateful for the opportunity to be a part of all these memorable moments. Here’s a comprehensive wrap-up of the key moments that defined the past 12 months. FUNLAYERS twinning EU project kicks off with a workshop The Functional Layered Materials for Advanced Applications – FUNLAYERS project consists of a twinning initiative aimed to propel INL’s research excellence in the field of layered materials whilst unfolding its tremendous potential applications for energy storage and spintronics, under the coordination of INL – International Iberian Nanotechnology Laboratory together with the other ALBA-CELLS and Max Planck Institute of Microstructure Physics (MPG) teams. Read the full update >> INL hosted the Horizon Europe BATT4EU Funding Opportunities event INL – International Iberian Nanotechnology Laboratory in collaboration with ANI – Agência Nacional de Inovação hosted the Horizon Europe BATT4EU Funding […]

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Solar energy solutions inspired by nature

Solar energy solutions inspired by nature

ADAPTATION is the new European-funded project, which involves collaborative efforts from Spain and Portugal. This Iberian consortium combines the scientific expertise from INL, Consejo Superior de Investigaciones Científicas (CSIC), University of Minho, and University of Vigo. ADAPTATION draws inspiration from nature, more precisely from photosynthesis. The project aims to develop an innovative technology to absorb solar energy for electricity generation while incorporating self-cooling capabilities to mitigate energy losses. Sara Núñez-Sánchez, researcher at the University of Minho and coordinator of the project, explains that “the survival of plants does not depend so much on the amount of energy they absorb but on how efficiently they transport that energy”. This mechanism is what the ADAPTATION project aims to mimic, creating a new concept for a solar energy conversion device. The efficiency of devices that convert energy into electricity, such as solar panels, tends to decrease as heat accumulates. “The integration of photovoltaic or solar energy capture technologies is incompatible with technologies that allow efficient temperature management”, says Pedro David García, a researcher at ICMM-CSIC. The Iberian team will focus on mimicking, at the molecular level, how natural photosynthetic tissues are organised to generate new materials at the nanoscale. “All the structures we […]

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Understanding quantum entanglement

Understanding quantum entanglement

INL researchers have recently published a scientific paper describing a new method to confirm the presence of quantum entanglement. Similar to electricity and magnetism, quantum entanglement is a natural phenomenon that plays a central role in the most fascinating aspects of quantum mechanics. Quantum entanglement is a peculiar and counterintuitive occurrence that describes the intricate connection between two subatomic particles, even when they are separated by large distances. Any alteration made to one of these particles will instantaneously impact the other, defying the conventional expectation that distance should limit such influences. The idea that quantum entanglement can be used as a resource is fundamental to fields like quantum computing, quantum sensing, and quantum communications. To make use of quantum entanglement, it is crucial to develop tools for investigating it, which can be particularly challenging at the nanoscale. INL researchers have recently described a new technique to identify quantum entanglement, by using state-of-the-art equipment – electron spin resonance using scanning tunnelling microscopy (STM). Joaquín Fernández-Rossier, Theory of Quantum Nanostructures research group leader, says that “our proposal adds a completely new functionality to STM, establishing a connection between quantum information and surface science”. This work was supported by the Quantum Portugal Initiative […]

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INL contributes to the NGS Agenda

INL contributes to the NGS Agenda

As part of Portugal’s Recovery and Resilience Plan (PRR), INL actively contributes to the NGS Agenda, engaging in various research initiatives spanning the entire battery value chain. This involves establishing a comprehensive battery ecosystem, encompassing the production of battery components and the exploration of novel materials and processes for battery manufacturing. Yesterday, INL hosted the NGS Networking Day, organised by dstgroup. The morning session featured two roundtable discussions addressing topics such as the ‘valorisation and advanced refining’ of batteries, and the installation and development of safer and sustainable ‘cells, modules, and components’. Before the lunch break, there was a dedicated moment to address crucial agenda management topics. The afternoon started with additional roundtable discussions covering ‘battery pack assembly’, ‘integration and applications,’ and the ‘recycling and second life’ aspects of batteries. Furthermore, participants had the opportunity to explore avenues for enhancing technical skills, advancing knowledge, and fostering education within the diverse partner organisations. Concluding the afternoon, the Battery Cluster PT introduced a new Technology Platform that will propel the industry to the forefront of the international battery sector. This event served as a valuable platform for all NGS Agenda partners to discuss significant matters, and collaborate in creating an innovative battery […]

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Enhancing nutrition for older adults through nanotechnology

Enhancing nutrition for older adults through nanotechnology

Aging often brings challenges such as alterations in taste, smell, chewing, and swallowing, leading to insufficient eating and malnutrition. To address these issues, INL scientists are actively developing advanced technologies for food fortification and customised textures, aiming to promote a more balanced diet for seniors. A particularly promising strategy involves the creation of personalised foods to meet the unique nutritional needs of the elderly. Arlete Marques, a PhD fellow supported by FCT, is developing her research in collaboration with INL and the Centre of Biological Engineering at the University of Minho. Arlete emphasises that “this approach not only ensures that seniors meet their nutritional requirements but also aligns with their individual preferences”. One aspect of this research focuses on crafting an alternative protein-based meat-like product tailored for older individuals with swallowing difficulties. The INL Food Processing and Nutrition research group explores nanotechnology to enrich the food with iron and folic acid. The group has developed micro and nanoparticles that can lead to a better absorption of the micronutrients in the digestive system. In terms of food texture, the team is working with Aspergillus oryzae, a filamentous fungus that is widely used in food fermentation, particularly in Asian countries. Aspergillus oryzae […]

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Solar-powered textiles in automotive innovation

Solar-powered textiles in automotive innovation

Exploring the integration of solar cells into textiles for the automobile industry presents an intriguing prospect. This innovation could extend to practical applications, such as using solar-charged fabrics to power electronic devices like phones, thereby enhancing the sustainability and functionality of future automotive designs. While textiles are primarily associated with clothing, they have a rich historical use in sailcloth, tents, and sacks. Leveraging textiles as substrates for solar cells could further expand their potential applications. However, the adoption of fabrics as photovoltaic substrates raises pertinent questions. Textiles must endure the necessary processing conditions to become photovoltaics; resulting solar textiles must withstand wear and tear, as well as washing and drying cycles. There might be a risk of solar cells compromising crucial physical or aesthetic features of textiles. Most commonly known photovoltaics typically consist of solar cells mounted on glass. However, their weight and fragility may pose challenges in certain applications. The exploration of lighter and more flexible solar cells presents potential advantages, including enhanced durability, cost-effectiveness, and resilience in harsh environments. “Integrating solar cells into textiles is technologically challenging,” explains Roma Raj, a researcher in the Nanochemistry research group. “A critical issue is the adhesion of thin photovoltaic films to […]

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