Filipa Lebre

Research Fellow
Nanosafety

Filipa is a Research Fellow in the Nanosafety Research Group, and her research focus on the complex interactions among the immunological system and different organs, using novel technologies and in house developed systems.

Filipa has a background in Pharmaceutical Sciences and holds a PhD in Pharmaceutical Technology from the Faculty of Pharmacy, University of Coimbra, focused on the development and optimization of a polymeric nasal vaccine against hepatitis B, to be used for mass immunization. She moved to Ireland during her postdoc to conduct her research at the interface between biomaterial and immunology, studying key aspects of immunomodulation by a relevant spectrum of materials, with applicability in the regenerative medicine field. In 2019, she was awarded an Industry Fellowship to work in collaboration with Johnson & Johnson, where she was responsible for the development of tailored 3D bioprinted in vitro models. Filipa collaborated with leading experts in different fields, resulting in 16 peer-reviewed papers in international journals.

Selected Publications

  • Lebre, Filipa, John B. Boland, Pedro Gouveia, Aoife L. Gorman, Mimmi LE Lundahl, Roisin I. Lynch, Fergal J. O’Brien, Jonathan Coleman, and Ed C. Lavelle
    Pristine graphene induces innate immune training
    Nanoscale 12, no. 20 (2020): 11192-11200
  • Lebre, Filipa, Damien Hanlon, John B. Boland, Jonathan Coleman, and Ed C. Lavelle
    Exfoliation in Endotoxin‐Free Albumin Generates Pristine Graphene with Reduced Inflammatory Properties
    Advanced Biosystems 2, no. 12 (2018): 1800102
  • Lebre, Filipa, MC Pedroso de Lima, Ed C. Lavelle, and O. Borges
    Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles
    International journal of pharmaceutics 552, no. 1-2 (2018): 7-15
  • Lebre, Filipa, Rukmani Sridharan, Michael J. Sawkins, Daniel J. Kelly, Fergal J. O’Brien, and Ed C. Lavelle
    The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation
    Scientific reports 7, no. 1 (2017): 1-13
  • Lebre, Filipa, G. Borchard, H. Faneca, M. C. Pedroso de Lima, and O. Borges
    Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice
    Molecular pharmaceutics 13, no. 2 (2016): 472-482