Bañobre Group
Nanomedicine (NM)’s research focuses on the development of diagnostic and therapeutic approaches towards an early and unequivocal diagnosis and treatment of cancer, inflammatory and neurological diseases. NM works in close collaboration with the clinic to enable translational medical research and to approach the end-user, in an attempt to offer a better prognosis and personalized treatment. To this aim, NM covers from fundamental research on the identification and validation of diseases’ biomarkers and cellular interactions, to a more applied cross-disciplinary research focused on the development of technologies and nanostructures (inorganic, organic, hybrid) for precision disease diagnosis, therapy and theranostics, ranging from low to high technology readiness levels (TRLs).
NM field of action comprises in vitro (2D, 3D, OoC), ex vivo and in vivo experimentation and evolves in the frontier between Chemistry, Materials Science, Biophysics, Engineering and Biology, always within an international framework.
Nanomedicine evolves in the frontier between different disciplines of knowledge, such as chemistry, materials science, physics and biology, always within an international framework.
Research lines:
- Theranostic probes
- Animal‐free validation platforms
Projects
Publications
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Polymeric Microneedles for Health Care Monitoring: An Emerging Trend
ACS SENSORS, 2024 -
Comprehensive characterization and development of multi-core shell superparamagnetic nanoparticles for controlled delivery of drugs and their kinetic release modelling
MATERIALS TODAY CHEMISTRY, 2023Enhanced alpha-amylase inhibition activity of amine-terminated PAMAM dendrimer stabilized pure copper-doped magnesium oxide nanoparticles
BIOMATERIALS ADVANCES, 2023Hybrid multi-core shell magnetic nanoparticles for wet peroxide oxidation of paracetamol: Application in synthetic and real matrices
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2023Bacteriophage Delivery Systems for Food Applications: Opportunities and Perspectives
VIRUSES-BASEL, 2023Complete genome sequence of a novel bacteriophage vB_Pci_PCMW57 infecting phytobacteria pseudomonas cichorii
MOLECULAR BIOLOGY REPORTS, 2023Levofloxacin-Loaded Microneedles Produced Using 3D-Printed Molds for Klebsiella Pneumoniae Biofilm Control
ADVANCED THERAPEUTICS, 2023Paving the way forward: Escherichia coli bacteriophages in a One Health approach
CRITICAL REVIEWS IN MICROBIOLOGY, 2023Redox double-switch cancer theranostics through Pt(iv) functionalised manganese dioxide nanostructures
NANOSCALE, 2023Sustainable fluorescent dye-faujasite zeolite systems as tools for cancer bioimaging
CHEMICAL ENGINEERING JOURNAL, 2023Targeted treatment of triple-negative-breast cancer through pH-triggered tumour associated macrophages using smart theranostic nanoformulations
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023Bacteriophage control of infectious biofilms
Bacteriophage therapy: from lab to clinical practice, Vol. 2734, p141-150. Ed. Azeredo J and Sillankorva S, eBook ISBN: 978-1-0716-3523-0 (Dec. 2023), print ISBN: 978-1-0716-3522-3 (Jan 2024), 2023Bacteriophage therapy: from lab to clinical practice
Bacteriophage therapy: from lab to clinical practice, Vol. 2734. Ed. Azeredo J and Sillankorva S, p. 3-12, eBook ISBN: 978-1-0716-3523-0 (Dec. 2023), print ISBN: 978-1-0716-3522-3 (Jan 2024), 2023Isolation of bacteriophages for clinically relevant bacteria
Bacteriophage therapy: from lab to clinical practice, Methods in Molecular Biology, Vol. 2734. Ed. Azeredo J and Sillankorva S, p. 3-12, eBook ISBN: 978-1-0716-3523-0 (Dec. 2023), print ISBN: 978-1-0716-3522-3 (Jan 2024), 2023Complete genome sequence of a novel bacteriophage vB_Pci_PCMW57 infecting phytobacteria pseudomonas cichorii
MOLECULAR BIOLOGY REPORTS, 2023Levofloxacin‐Loaded Microneedles Produced Using 3D‐Printed Molds for Klebsiella Pneumoniae Biofilm Control
Advanced Therapeutics, 2023 -
Natural biopolymer scaffolds for bacteriophage delivery in the medical field
In Advances in biomedical polymers and composites: Materials and applications, 1st Edition (September 14, 2022), Eds. Kunal Pal, Sarika Verma, Pallab Datta, Ananya Barui, S.A.R. Hashmi, Avanish Srivastava, p: 760-786, Elsevier 2022, 2022Bioimaging of Lysosomes with a BODIPY pH-Dependent Fluorescent Probe
MOLECULES, 2022Insights into the effect of magnetic confinement on the performance of magnetic nanocomposites in magnetic hyperthermia and magnetic resonance imaging
ACS APPLIED NANO MATERIALS, 2022Antibiofilm Efficacy of the Pseudomonas aeruginosa Pbunavirus vB_PaeM-SMS29 Loaded onto Dissolving Polyvinyl Alcohol Microneedles
VIRUSES-BASEL, 2022Ex vivo transtympanic permeation of the liposome encapsulated S. pneumoniae endolysin MSlys
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2022Magnetic Solid Nanoparticles and Their Counterparts: Recent Advances towards Cancer Theranostics
PHARMACEUTICS, 2022Identification of the Bacterial Pathogens in Children with Otitis Media: A Study in the Northwestern Portuguese District of Braga
MICROORGANISMS, 2022Implication of a gene deletion on a Salmonella Enteritidis phage growth parameters
VIRUS RESEARCH, 2022Magnetic ferrogels based on crosslinked xanthan and iron oxide nanoparticles: preparation and physico-chemical characterization
CHEMICAL ENGINEERING COMMUNICATIONS, 2022Novel time-domain NMR-based traits for rapid, label-free Olive oils profiling
NPJ SCIENCE OF FOOD, 2022Magnetic lipid nanovehicles synergize the controlled thermal release of chemotherapeutics with magnetic ablation while enabling non-invasive monitoring by MRI for melanoma theranostics
BIOACTIVE MATERIALS, 2022PLGA-Based Composites for Various Biomedical Applications
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022Editorial: Phage-bacteria interplay: Future therapeutic approaches against antibiotic resistant bacteria
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022Synthesis of a KIT-6 mesoporous sulfonic acid catalyst to produce biodiesel from cashew nut oil
BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING, 2022A Review of the Advances and Challenges in Measuring the Thermal Conductivity of Nanofluids
NANOMATERIALS, 2022Suggestion for a new bacteriophage genus for the Klebsiella pneumoniae phage vB_KpnS-Carvaje
CURRENT GENETICS, 2022The integration of spheroids and organoids into organ-on-a-chip platforms for tumour research: A revie
Bioprinting, 2022 -
Targeting Nanomaterials to Head and Neck Cancer Cells Using a Fragment of the Shiga Toxin as a Potent Natural Ligand
CANCERS, 2021Graphene-Based Magnetic Nanoparticles for Theranostics: An Overview for Their Potential in Clinical Application
NANOMATERIALS, 2021PHBV films loaded with FO1 bacteriophage using polyvinyl alcohol-based nanofibers and coatings: a comparative study
Innovative Food Science and Emerging Technologies, 69:102646, 2021Extrinsic room-temperature ferromagnetism in MoS2
JOURNAL OF MATERIALS SCIENCE, 2021The clinical path to deliver encapsulated phages and lysins
FEMS MICROBIOLOGY REVIEWS, 2021Pseudomonas aeruginosa PAO 1 In Vitro Time–Kill Kinetics Using Single Phages and Phage Formulations—Modulating Death, Adaptation, and Resistance
ANTIBIOTICS-BASEL, 2021A novel amino phosphonate-coated magnetic nanoparticle as MRI contrast agent
APPLIED SURFACE SCIENCE, 2021A novel and extremely stable nanofluid based on iron oxide nanoparticles: Experimental investigations on the thermal performance
THERMAL SCIENCE AND ENGINEERING PROGRESS, 2021Challenges and recommendations for magnetic hyperthermia characterization measurements
International Journal of Hyperthermia, 38(1), 447–460, 2021Effective production of multifunctional magnetic-sensitive biomaterial by an extrusion-based additive manufacturing technique
BIOMEDICAL MATERIALS, 2021Potential G-quadruplexes and i-Motifs in the SARS-CoV-2
PLOS ONE, 2021Ratiometric magnetic resonance imaging: Contrast agent design towards better specificity and quantification
COORDINATION CHEMISTRY REVIEWS, 2021Smart magnetic resonance imaging-based theranostics for cancer
THERANOSTICS, 2021Solid Lipid Particles for Lung Metastasis Treatment
PHARMACEUTICS, 2021Stimulation and Suppression of the Innate Immune System through Nanotechnology
ACS APPLIED NANO MATERIALS, 2021Sustained Release of a Streptococcus pneumoniae Endolysin from Liposomes for Potential Otitis Media Treatment
ACS INFECTIOUS DISEASES, 2021Xanthan-Fe3O4 Nanoparticle Composite Hydrogels for Non-Invasive Magnetic Resonance Imaging and Magnetically Assisted Drug Delivery
ACS APPLIED NANO MATERIALS, 2021G-Quadruplex DNA as a Target in Pathogenic Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its Mode of Action
JOURNAL OF MEDICINAL CHEMISTRY, 2021Magnetic Field Mapping Around Individual Magnetic Nanoparticle Agglomerates Using Nitrogen-Vacancy Centers in Diamond
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 2021Magnetoliposomes Based on Shape Anisotropic Calcium/Magnesium Ferrite Nanoparticles as Nanocarriers for Doxorubicin
PHARMACEUTICS, 2021Experimental Studies of the Sedimentation, Stability and Thermal Conductivity of Two Different Nanofluids
Eng. Proc. 2021, 4, 35, 2021 -
The Protective Effect of Staphylococcus epidermidis Biofilm Matrix against Phage Predation
VIRUSES-BASEL, 2020A multifunctional nanomedicine platform for co-delivery of methotrexate and mild hyperthermia towards breast cancer therapy
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020Structure of Manganese Oxide Nanoparticles Extracted via Pair Distribution Functions
CONDENSED MATTER, 2020Mapping intracellular thermal response of cancer cells to magnetic hyperthermia treatment
NANOSCALE, 2020Evaluation of Novel Doxorubicin-Loaded Magnetic Wax Nanocomposite Vehicles as Cancer Combinatorial Therapy Agents
PHARMACEUTICS, 2020(Para)magnetic hybrid nanocomposites for dual MRI detection and treatment of solid tumours
CHEMICAL COMMUNICATIONS, 2020Inactivation of Pseudomonas aeruginosa in mineral water by DP1 bacteriophage immobilized on ethylene-vinyl acetate copolymer used as seal caps of plastic bottles
JOURNAL OF APPLIED POLYMER SCIENCE, 2020Porous composites based on cellulose acetate and alfa-hematite with optical and antimicrobial properties.
Carbohydrate Polymers 2020, 241, 116362, 2020Synthesis, Characterization, and Evaluation of Superparamagnetic Doped Ferrites as Potential Therapeutic Nanotools
CHEMISTRY OF MATERIALS, 2020Bacteriophages for Chronic Wound Treatment: From Traditional to Novel Delivery Systems
VIRUSES-BASEL, 2020Chemical preparation, crystal structure, Hirshfeld surface analysis, spectroscopy, DFT studies, thermal decomposition and magnetic measurements of (C4H12N2)[FeCl3(H2O)(3)]Cl-2
INORGANIC CHEMISTRY COMMUNICATIONS, 2020Entrapment of a phage cocktail and cinnamaldehyde on sodium alginate emulsion-based films to fight food contamination by Escherichia coli and Salmonella Enteritidis
FOOD RESEARCH INTERNATIONAL, 2020Characterization of MSlys, the endolysin of Streptococcus pneumoniae phage MS1
Biotechnology Reports, 2020Morphology and water flux of produced cellulose acetate membranes reinforced by the design of experiments (DOE)
CARBOHYDRATE POLYMERS, 2020Organ-on-a-Chip: A Preclinical Microfluidic Platform for the Progress of Nanomedicine
SMALL, 2020Magnetic Hybrid Wax Nanocomposites as Externally Controlled Theranostic Vehicles: High MRI Enhancement and Synergistic Magnetically Assisted Thermo/Chemo Therapy
Chemistry A European Journal, 2020 -
G4-iM Grinder: when size and frequency matter. G-Quadruplex, i-Motif and higher order structure search and analysis tool
NAR GENOMICS AND BIOINFORMATICS, 2019Electrochemical Immunosensor for TNF alpha-Mediated Inflammatory Disease Screening
ACS CHEMICAL NEUROSCIENCE, 2019Bacteriophage phi IBB-PF7A loaded on sodium alginate-based films to prevent microbial meat spoilage
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2019Combining magnetic hyperthermia and dual T1/T2 MR imaging using highly versatile iron oxide nanoparticles
DALTON TRANSACTIONS, 2019Effectiveness and Safety of a Nontargeted Boost for a CXCR4-Targeted Magnetic Hyperthermia Treatment of Cancer Cells
ACS OMEGA, 2019Enhanced performance of cobalt ferrite encapsulated in graphitic shell by means of AC magnetically activated catalytic wet peroxide oxidation of 4-nitrophenol
CHEMICAL ENGINEERING JOURNAL, 2019Recent Progress on Manganese-Based Nanostructures as Responsive MRI Contrast Agents
CHEMISTRY-A EUROPEAN JOURNAL, 2019Synthesis, characterization and in vitro validation of a magnetic zeolite nanocomposite with T-2-MRI properties towards theranostic applications
JOURNAL OF MATERIALS CHEMISTRY B, 2019Targeting tumor cells and neovascularization using RGD-functionalized magnetoliposomes
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2019Antibiotic Alternatives and Combinational Therapies for Bacterial Infections - eBook
Frontiers in Microbiology, 2019Escherichia coli and Salmonella Enteritidis dual-species biofilms: interspecies interactions and antibiofilm efficacy of phages
SCIENTIFIC REPORTS, 2019Synthesis, characterization and evaluation of deacetylated xanthan derivatives as new excipients in the formulation of chitosan-based polyelectrolytes for the sustained release of tramadol
SAUDI PHARMACEUTICAL JOURNAL, 2019Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications
NANOMATERIALS, 2019